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A key feature to look for when making the choice for the Best Registry Fix software for your preferences would be the ability to automatically backup and restore the registry BEFORE you go ahead with the cleaning process. 

Registry cleaners that have this function sometimes have this option disabled and therefore would have the user go into the settings area to enable this very necessary function.  Also the restore function is the other side of the coin for the back up and is necessary in the case that the computer user would want to revert to the old registry configuration.